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Anti-HES-6 Antibody

品牌：Antibodies

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规格：50µl

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Anti-HES-6 Antibody

商品详情参考文献相关资料

Name:	Anti-HES-6 Antibody See all HES6 primary antibodies
Description:	Rabbit polyclonal antibody to HES-6
Specificity:	HES-6 Polyclonal Antibody detects endogenous levels of HES-6 protein.
Applications:	WB, IHC, ELISA
Reactivity:	Human
Immunogen:	Synthesized peptide derived from the N-terminal region of human HES-6.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1mg / ml
Formulation:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage:	Store at -20?C / 1 year

Function:	Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation (By similarity).
Cellular locations:	Nucleus.
Database Links:	Entrez Gene: 55502?Human Omim: 610331?Human SwissProt: Q96HZ4?Human Unigene: 42949?Human
Synonyms:	bHLHb41 Antibody bHLHc23 Antibody C HAIRY1 Antibody Class B basic helix-loop-helix protein 41 Antibody Hairy and enhancer of split 6 Antibody Hairy/enhancer of split 6, Drosophila, homolog of, 6 Antibody HES 6 Antibody hes family bHLH transcription factor 6 Antibody HES6 Antibody Transcription cofactor HES6 Antibody
Information:	Target information shown above is from the UniProt Consortium.