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Anti-SEMA4C Antibody

品牌：Antibodies

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规格：100µl

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Anti-SEMA4C Antibody

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Name:	Anti-SEMA4C Antibody See all SEMA4C primary antibodies
Description:	Rabbit polyclonal antibody to SEMA4C
Specificity:	The antibody detects endogenous levels of total SEMA4C protein.
Applications:	IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to residues near the C terminal of human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.1mg / ml
Formulation:	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage:	Store at -20?C

Function:	Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Sequence Similarities:	Belongs to the semaphorin family.
Cellular locations:	Cell junction > Synapse > Postsynaptic cell membrane > Postsynaptic density. Cytoplasmic vesicle > Secretory vesicle > Synaptic vesicle membrane.
Database Links:	Entrez Gene: 54910?Human Omim: 604462?Human SwissProt: Q9C0C4?Human Unigene: 516220?Human
Synonyms:	KIAA1739 Antibody M-SEMA-F Antibody S4c Antibody SEM4C_HUMAN Antibody Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C Antibody SEMA4C Antibody SEMACL1 Antibody SEMAF Antibody SEMAI Antibody Semaphorin-4C Antibody UNQ5855/PRO34487 Antibody
Information:	Target information shown above is from the UniProt Consortium.