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Anti-LMNB2 Antibody |产品详情|进口橙子视频旧款采购网




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    Anti-LMNB2 Antibody
    品牌:Antibodies
    货号:
    规格:50µl
    货期:

    Anti-LMNB2 Antibody

    商品详情 参考文献 相关资料
    Name: Anti-LMNB2 Antibody
    See all LMNB2 primary antibodies
    Description: Rabbit polyclonal antibody to LMNB2.
    Applications: WB, IHC, IF
    Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100.
    Reactivity: Human, Mouse, Rat
    Immunogen: Recombinant protein of human LMNB2.
    Protein Length: 600
    Host: Rabbit
    Clonality: Polyclonal
    Isotype: IgG
    Conjugate: Unconjugated
    Purification: Affinity purification.
    Product Form: Liquid
    Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
    Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
    Function: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
    Involvement in Disease: Partial acquired lipodsystrophy: A rare childhood disease characterized by loss of subcutaneous fat from the face and trunk. Fat deposition on the pelvic girdle and lower limbs is normal or excessive. Most frequently, onset between 5 and 15 years of age. Most affected subjects are females and some show no other abnormality, but many develop glomerulonephritis, diabetes mellitus, hyperlipidemia, and complement deficiency. Mental retardation in some cases. APLD is a sporadic disorder of unknown etiology.

    Epilepsy, progressive myoclonic 9: An autosomal recessive form of progressive myoclonic epilepsy, a rare disease initially responsive to antiepileptic drugs which over time becomes refractory and can be associated with cognitive decline. EPM9 features include myoclonus, tonic-clonic seizures, ataxia, and psychomotor development.
    Sequence Similarities: Belongs to the intermediate filament family.
    Post-Translational Modification: B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations.
    Cellular locations: Nucleus inner membrane.
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