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Anti-GEMIN2 Antibody |产品详情|进口橙子视频旧款采购网




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    Anti-GEMIN2 Antibody
    品牌:Antibodies
    货号:
    规格:50µl
    货期:

    Anti-GEMIN2 Antibody

    商品详情 参考文献 相关资料
    Name: Anti-GEMIN2 Antibody
    See all GEMIN2 primary antibodies
    Description: Rabbit polyclonal antibody to GEMIN2.
    Applications: WB, IHC, IF
    Dilutions: WB: 1:500 - 1:1000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200.
    Reactivity: Human, Mouse, Rat
    Immunogen: A synthetic peptide of human GEMIN2.
    Protein Length: 280
    Host: Rabbit
    Clonality: Polyclonal
    Isotype: IgG
    Conjugate: Unconjugated
    Purification: Affinity purification.
    Product Form: Liquid
    Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
    Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
    Function: The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
    Sequence Similarities: Belongs to the gemin-2 family.
    Cellular locations: Nucleus > Gem. Cytoplasm.

    Localized in subnuclear structures next to coiled bodies, called gems, which are highly enriched in spliceosomal snRNPs. Also found in the cytoplasm.
    Database Links:
  • Entrez Gene: 8487?Human
  • Entrez Gene: 66603?Mouse
  • Entrez Gene: 84404?Rat
  • Omim: 602595?Human
  • SwissProt: O14893?Human
  • SwissProt: Q9CQQ4?Mouse
  • SwissProt: Q9QZP1?Rat
  • Unigene: 652307?Human
  • Unigene: 35353?Mouse
  • Unigene: 34143?Rat
  • Synonyms:
  • Component of gems 2 Antibody
  • Gem (nuclear organelle) associated protein 2 Antibody
  • Gem associated protein 2 Antibody
  • GEMI2_HUMAN Antibody
  • Gemin 2 Antibody
  • Gemin-2 Antibody
  • gemin2 Antibody
  • SIP 1 Antibody
  • SIP-1 Antibody
  • SIP1 Antibody
  • SIP1 delta Antibody
  • SIP1-delta Antibody
  • SMN interacting protein 1 Antibody
  • SMN interacting protein 1 delta Antibody
  • SMN-interacting protein 1 Antibody
  • Survival interacting protein 1 Antibody
  • Survival of motor neuron protein interacting protein 1 Antibody
  • Survival of motor neuron protein-interacting protein 1 Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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