Anti-Pregnancy associated plasma protein A (human, PAPP-A) ABS 006-24 ABS 006-24|产品详情|进口橙子视频旧款采购网

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Anti-Pregnancy associated plasma protein A (human, PAPP-A) ABS 006-24

品牌：

货号：ABS 006-24

规格：200 µg

货期：

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Anti-Pregnancy associated plasma protein A (human, PAPP-A)

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Cat. No.: ABS 006-24
Product name: Anti-Pregnancy associated plasma protein A (human, PAPP-A)
Description: Mouse monoclonal antibody
Specificity: ABS 006-24 is specific for native human PAPP-A. Heat and SDS denatured PAPP-A is also recognized, but not acid treated PAPP-A .
Immunogen: Purified human PAPP-A
Application: ELISA, WB, IHC
Species reactivity (positive): Human
Species reactivity (negative): Not determined
Subclass: IgG1/k
Gene ID: 5069
Clone number: PAPP A 1-24
Epitope: The epitope of ABS 006-24 is different from BTE 004-09 and ABS 006-01. The epitope is located on the PAPP-A subunit of the heterotetramer.
Content: Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification: Protein-A purified
Form: Liquid
Solvent: 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage: 4-8ºC without exposure to light. No precautions necessary during handling.
Target: Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterotetrameric glycoprotein of approximately 500 kDa, which was first discovered in serum from pregnant women. The hetreotetramer consists of two PAPP-A subunits and two proMBP subunits. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down’s syndrome (trisomy 21).

Application 1: ELISA
BTE 004-09 as coating antibody and biotinylated ABS 006-24 as detection antibody is a good combination for sandwich ELISA.
Application 2: WB
ABS 006-24 only detecs unreduced PAPP-A in Western Blotting.
Application 3: IHC
ABS 006-24 gives the strongest singal in IHC compared to ABS 006-01 and BTE 004-09.

Immunohistochemical staining of a formalin-fixed, paraffin-embedded placental tissue with ABS 006-24